<SEC-DOCUMENT>0001735276-23-000018-index.html : 20230227
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<ACCEPTANCE-DATETIME>20230227161302
ACCESSION NUMBER:		0001735276-23-000018
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20230223
FILED AS OF DATE:		20230227
DATE AS OF CHANGE:		20230227

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			PYOTT DAVID E I
		CENTRAL INDEX KEY:			0001051578

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36407
		FILM NUMBER:		23674963

	MAIL ADDRESS:	
		STREET 1:		C/O ALLERGAN
		STREET 2:		2525 DUPONT DRIVE
		CITY:			IRVINE
		STATE:			CA
		ZIP:			92612

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ALNYLAM PHARMACEUTICALS, INC.
		CENTRAL INDEX KEY:			0001178670
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				770602661
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		675 WEST KENDALL STREET
		STREET 2:		HENRI A. TERMEER SQUARE
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142
		BUSINESS PHONE:		(617) 551-8200

	MAIL ADDRESS:	
		STREET 1:		675 WEST KENDALL STREET
		STREET 2:		HENRI A. TERMEER SQUARE
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ALNYLAM PHARMACEUTICALS INC
		DATE OF NAME CHANGE:	20020724
</SEC-HEADER>
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<TYPE>4
<SEQUENCE>1
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<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
Document 1 - file: edgardoc.html

Document 1 - RAW XML: edgardoc.xml

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<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>pyott_20231206poa.txt
<DESCRIPTION>EDGAR SUPPORTING DOCUMENT
<TEXT>
Document 2 - file: pyott_20231206poa.txt

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