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Summary of Significant Accounting Policies (Tables)
6 Months Ended
Jun. 30, 2016
Accounting Policies [Abstract]  
Research and Development Expenses and Reimbursements Due
Information about the Company’s research and development expenses and reimbursements due under collaboration arrangements for the three and six months ended June 30, 2016 and 2015, is presented as follows:
 
 
Three Months Ended June 30,
 
Six Months Ended June 30,
 
 
2016
 
2015
 
2016
 
2015
Research and development expense, gross
 
$
6,827

 
$
3,820

 
$
11,789

 
$
7,801

Less: Reimbursement of research and development expense
 
168

 
538

 
387

 
732

     Research and development expense, net of reimbursements
 
$
6,659

 
$
3,282

 
$
11,402

 
$
7,069

Summary of Antidilutive Securities Excluded from Computation of Weighted Average Common Stock Outstanding
The following potentially dilutive shares of common stock have not been included in the computation of diluted net loss per share for all periods as the result would be anti-dilutive.
 
June 30,
 
 
2016
 
2015
 
Warrants to purchase Series C-1 Preferred
14,033

 
14,033

 
Warrants to purchase common stock
4,218,750

 

 
Stock options
1,804,473

 
1,153,369