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Stock-based Compensation - Stock Option Activity (Detail) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Number of Shares    
Beginning balance - Outstanding (shares) 830,343  
Granted (shares) 874,050  
Forfeited/expired (shares) (162,267)  
Ending balance - Outstanding (shares) 1,542,126 830,343
Exercisable (shares) 739,332  
Vested or expected to vest (shares) 1,542,126  
Weighted- Average Exercise Price    
Beginning balance - Outstanding (in dollars per share) $ 21.52  
Granted (in dollars per share) 7.30  
Forfeited/expired (in dollars per share) 7.95  
Ending balance - Outstanding (in dollars per share) 14.89 $ 21.52
Exercisable (in dollars per share) 22.73  
Vested or expected to vest (in dollars per share) $ 14.89  
Weighted- Average Remaining Contractual Life (in years)    
Balance - Outstanding 7 years 5 months 12 days 7 years 8 months 15 days
Exercisable 5 years 10 months 28 days  
Vested or expected to vest 7 years 5 months 12 days  
Aggregate Intrinsic Value ($000)    
Balance - Outstanding $ 42 $ 96
Exercisable 11  
Vested and expected to vest $ 42