Income Taxes - Schedule of Deferred Tax Assets and Liabilities (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Income Tax Disclosure [Abstract]
Accrued expenses	$ 1,264	$ 148
Stock-based compensation	2,554	2,591
Lease liability	789	935
Other	(757)	(823)
Net operating loss carryforwards	80,453	70,936
Research and development credits	6,839	5,291
Total deferred tax assets	91,142	79,078
Valuation allowances	(91,142)	(79,078)
Net deferred tax assets	$ 0	$ 0