Income Taxes - Additional Information (Detail) - USD ($)	1 Months Ended			12 Months Ended
	Feb. 28, 2022	Apr. 30, 2021	Apr. 30, 2020	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2017
Operating Loss Carryforwards [Line Items]
Income tax expense (benefit)				$ (3,088,000)	$ (3,148,000)
Loss before taxes				$ 35,954,000	$ 58,333,000
Corporate income tax rate				21.00%	21.00%
Temporary expensing for certain business assets and property, percent				100.00%
Maximum deduction percentage of pre-NOL taxable income				80.00%
Unrecognized tax benefits that would impact effective tax rate				$ 0
Significant change in unrecognized tax benefits is reasonably possible, amount of unrecorded benefit				0
Income tax examination, penalties and interest accrued				$ 0
Maximum
Operating Loss Carryforwards [Line Items]
Corporate income tax rate				21.00%		35.00%
Exclusive License And Collaboration Agreement
Operating Loss Carryforwards [Line Items]
Income tax expense (benefit)				$ 1,100,000
Revenue recognized				1,100,000
Fixed upfront cash payment				10,000,000.0
Federal
Operating Loss Carryforwards [Line Items]
Net operating loss carryforward				348,400,000	$ 294,400,000
Tax credit carryforward				6,600,000
NOLs subject to expiration				169,600,000
NOLs subject not to expiration				$ 55,700,000	52,000,000.0
NOLs expiration date				Dec. 31, 2037
Net operating loss carryforwards expiration year				2022
State
Operating Loss Carryforwards [Line Items]
Net operating loss carryforward				$ 186,300,000	202,700,000
Net operating loss carryforwards expiration year				2019
State | New Jersey
Operating Loss Carryforwards [Line Items]
Income tax expense (benefit)				$ (4,100,000)	$ (3,100,000)
Cash receipt from the sale of state NOLs		$ 4,100,000	$ 3,100,000
Maximum selling value of unused net operating losses and research and development tax credit to profitable tax payers.				20,000,000.0
Amount received from the program				$ 14,000,000.0
State | Subsequent Event | New Jersey
Operating Loss Carryforwards [Line Items]
Cash receipt from the sale of state NOLs	$ 4,700,000