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Description of Business and Basis of Preparation - Additional Information (Detail)
Jan. 08, 2021
USD ($)
Jan. 01, 2021
USD ($)
Oct. 01, 2020
USD ($)
Jul. 17, 2020
shares
Jul. 16, 2020
shares
Dec. 31, 2021
USD ($)
shares
Dec. 31, 2020
USD ($)
shares
Dec. 31, 2019
shares
Jun. 18, 2019
shares
Jun. 17, 2019
shares
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]                    
Accumulated deficit | $           $ 359,479,000 $ 326,613,000      
Cash and cash equivalents | $           $ 104,484,000 $ 93,041,000      
Shelf registration maximum equity initial offering price | $     $ 200,000,000.0              
Reverse stock split, ratio         0.1          
Common stock, shares authorized (in shares) | shares       100,000,000 250,000,000 100,000,000 100,000,000   250,000,000 125,000,000
Common stock, shares issued (in shares) | shares       10,508,302 105,083,291 28,705,334 19,663,698      
Common stock, shares outstanding (in shares) | shares       10,508,302 105,083,291 28,705,334 19,663,698      
Stock issued during period as result of reverse stock splits | shares       0 0          
Common Stock                    
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]                    
Common stock, shares outstanding (in shares) | shares           28,705,334 19,663,698 9,741,372    
Sales Agreement | Common Stock                    
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]                    
Shelf registration maximum equity initial offering price | $   $ 50,000,000.0                
January 2021 Shelf Registration                    
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]                    
Shelf registration maximum equity initial offering price | $ $ 200,000,000.0