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Stock-based Compensation - Stock Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
6 Months Ended 12 Months Ended
Jun. 30, 2017
Dec. 31, 2016
Number of Shares    
Beginning balance - Outstanding (shares) 1,819,444  
Granted (shares) 982,803  
Exercised (shares) 0  
Canceled (shares) (73)  
Ending balance - Outstanding (shares) 2,802,174 1,819,444
Exercisable (shares) 1,331,565  
Vested or expected to vest (shares) 2,802,174  
Weighted- Average Exercise Price    
Beginning balance - Outstanding (in dollars per share) $ 7.52  
Granted (in dollars per share) 3.07  
Exercised (in dollars per share) 0.00  
Canceled (in dollars per share) 9.64  
Ending balance - Outstanding (in dollars per share) 5.96 $ 7.52
Exercisable (in dollars per share) 7.72  
Vested or expected to vest (in dollars per share) $ 5.96  
Weighted- Average Remaining Contractual Life (in years)    
Balance - Outstanding 7 years 1 month 24 days 6 years 11 months 23 days
Exercisable 5 years 8 months 27 days  
Vested and expected to vest 7 years 1 month 24 days  
Aggregate Intrinsic Value ($000)    
Balance - Outstanding $ 2 $ 32
Exercisable 0  
Vested and expected to vest $ 2