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Stockholder's Equity - Additional Information (Detail) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
Sep. 30, 2016
Jun. 21, 2016
Jul. 31, 2006
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Dec. 31, 2016
Equity [Abstract]                
Common stock, par value (in dollars per share)       $ 0.001   $ 0.001   $ 0.001
Common stock, shares authorized (in shares)       125,000,000   125,000,000   125,000,000
Common stock, shares issued (in shares)       26,478,051   26,478,051   24,609,411
Schedule of Capitalization, Equity [Line Items]                
Number of warrants issued to purchase common stock (in shares)       14,033   14,033   14,033
Warrant liability fair value adjustment       $ 2,924,000 $ 101,000 $ 4,447,000 $ 101,000  
Warrant liability       $ 2,154,000   $ 2,154,000   $ 6,601,000
Warrants to purchase common stock associated with Loan Agreement                
Schedule of Capitalization, Equity [Line Items]                
Number of warrants issued to purchase common stock (in shares) 122,435     122,435   122,435    
Exercise price of warrants (in dollars per share) $ 3.6754     $ 3.6754   $ 3.6754    
Warrant expiration period 5 years         5 years    
June 2016 Public Offering                
Schedule of Capitalization, Equity [Line Items]                
Number of warrants issued to purchase common stock (in shares)   4,218,750            
Exercise price of warrants (in dollars per share)   $ 3.00            
Number of shares received per warrant (in shares)   0.45            
Warrant expiration period   5 years            
Series C-1 Convertible Preferred Stock [Member]                
Schedule of Capitalization, Equity [Line Items]                
Number of warrants issued to purchase common stock (in shares)     196,923          
Exercise price of warrants (in dollars per share)     $ 3.25          
Fair value of warrants     $ 500,000          
Derivative Liability       $ 0   $ 0   $ 0
Common Stock                
Schedule of Capitalization, Equity [Line Items]                
Number of warrants issued to purchase common stock (in shares)     14,033          
Exercise price of warrants (in dollars per share)     $ 45.61