Stock-based Compensation (Tables)

3 Months Ended

Mar. 31, 2017

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Schedule of Share-based Compensation, Stock Options, Activity

The activity for the 2009 Stock Option Plan, 2014 Plan and 2015 Plan for the three months ended March 31, 2017, is summarized as follows:

	Number of Shares		Weighted- Average Exercise Price		Weighted- Average Remaining Contractual Life (in years)	Aggregate Intrinsic Value ($000)
Outstanding — December 31, 2016	1,819,444		$	7.52	6.98	$	32
Granted	950,658		$	3.10
Exercised	—		$	—
Canceled	(73	)	$	9.64
Outstanding — March 31, 2017	2,770,029		$	6.00	7.36	$	14
Exercisable — March 31, 2017	1,138,970		$	8.26	5.49	$	9
Vested or expected to vest — March 31, 2017	2,770,029		$	6.00	7.36	$	14

RSU activity under the 2014 Plan for the three months ended March 31, 2017, is summarized as follows:

	Number of Shares	Weighted Average Grant Date Fair Value Per Share
Non-vested at December 31, 2016	—	—
Granted	44,032	$	3.10
Vested	—	—
Forfeited	—	—
Non-vested at March 31, 2017	44,032	—

Stock-Based Compensation Expense Related to Stock Options

Stock-based compensation expense related to stock options is included in the following line items in the accompanying statements of operations (dollars in thousands):

	Three Months Ended March 31,
	2017		2016
Research and development	$	94	$	70
Selling, general and administrative	302		204
Total stock-based compensation expense	$	396	$	274