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Stock-based Compensation (Tables)
 12 Months Ended
Dec. 31, 2023
Share-Based Payment Arrangement [Abstract]  
Assumptions Used To Estimate Fair Value of Options The assumptions used to estimate fair value and the resulting grant date fair values are as follows:

 

 

 

Employees

 

 

Non-employee

 

 

 

Years Ended December 31,

 

 

Years Ended December 31,

 

 

 

2023

 

 

2022

 

 

2023

 

 

2022

 

Weighted average expected volatility

 

 

74.77

%

 

 

73.80

%

 

 

80.12

%

 

 

74.20

%

Weighted average risk-free interest rate

 

 

3.98

%

 

 

2.45

%

 

 

3.89

%

 

 

3.18

%

Weighted average expected term (in years)

 

 

6.04

 

 

 

6.04

 

 

 

5.50

 

 

 

5.63

 
Schedule of Share-based Compensation, Stock Options, Activity

The activity for the 2009 Plan, 2014 Plan and 2015 Plan for the years ended December 31, 2023 is summarized as follows:

 

 

 

Number
of
Shares

 

 

Weighted-
Average
Exercise
Price

 

 

Weighted-
Average
Remaining
Contractual
Life (in years)

 

 

Aggregate
Intrinsic
Value ($000)

 

Outstanding — December 31, 2022

 

 

1,740,308

 

 

$

12.21

 

 

 

6.16

 

 

$

—

 

Granted

 

 

303,000

 

 

$

1.87

 

 

 

 

 

 

 

Forfeited/expired

 

 

(175,513

)

 

$

10.21

 

 

 

 

 

 

 

Outstanding — December 31, 2023

 

 

1,867,795

 

 

$

10.72

 

 

 

6.10

 

 

$

184

 

Exercisable — December 31, 2023

 

 

1,320,943

 

 

$

13.92

 

 

 

5.03

 

 

$

53

 

Vested or expected to vest —December 31, 2023

 

 

1,867,795

 

 

$

10.72

 

 

 

6.10

 

 

$

184

 

 
Schedule of Restricted Stock Units ("RSU") Activity

Restricted stock unit ("RSU") activity under the 2014 Plan and 2015 Plan for the years ended December 31, 2023, is summarized as follows:

 

 

 

Number of
Shares

 

 

Weighted
Average
Grant Date
Fair Value
Per Share

 

Non-vested at December 31, 2022

 

 

633,270

 

 

$

5.29

 

Granted

 

 

1,929,575

 

 

$

1.79

 

Vested

 

 

(302,561

)

 

$

5.01

 

Forfeited

 

 

(373,910

)

 

$

2.62

 

Non-vested at December 31, 2023

 

 

1,886,374

 

 

$

2.28

 
Stock-Based Compensation Expense Related to Stock Options and Stock Awards

Stock-based compensation expense related to stock options and stock awards is included in the following line items in the accompanying statements of operations (in thousands):

 

 

 

Years Ended December 31,

 

 

 

2023

 

 

2022

 

Research and development

 

$

873

 

 

$

1,076

 

Selling, general and administrative

 

 

1,751

 

 

 

2,436

 

Total stock-based compensation expense

 

$

2,624

 

 

$

3,512