Michael Gregory, Managing Member

SCHEDULE 13G/A 0000919574-25-006940 0001791827 XXXXXXXX LIVE 8 Common Stock, par value $0.001 per share 12/31/2025 0001178253 Scynexis, Inc. 811292200 1 Evertrust Plaza 13th Floor Jersey City NJ 07302-6548 Rule 13d-1(c) Avidity Partners Management LP b DE 0.00 4426565.00 0.00 4426565.00 4426565.00 N 9.9 IA PN Avidity Partners Management (GP) LLC b DE 0.00 4426565.00 0.00 4426565.00 4426565.00 N 9.9 OO Avidity Capital Partners Fund (GP) LP b DE 0.00 4426565.00 0.00 4426565.00 4426565.00 N 9.9 PN Avidity Capital Partners (GP) LLC b DE 0.00 4426565.00 0.00 4426565.00 4426565.00 N 9.9 OO Avidity Master Fund LP b E9 0.00 852750.00 0.00 852750.00 852750.00 N 2.0 PN Avidity Private Master Fund I LP b E9 0.00 3573815.00 0.00 3573815.00 3573815.00 N 8.1 PN Michael Gregory b X1 0.00 4426565.00 0.00 4426565.00 4426565.00 N 9.9 HC IN Scynexis, Inc. 1 Evertrust Plaza, 13th Floor, Jersey City, New Jersey 07302-6548 Avidity Partners Management LP Avidity Partners Management (GP) LLC Avidity Capital Partners Fund (GP) LP Avidity Capital Partners (GP) LLC Avidity Master Fund LP Avidity Private Master Fund I LP Michael Gregory Avidity Partners Management LP 2828 N Harwood Street, Suite 1220 Dallas, Texas 75201 United States of America Avidity Partners Management (GP) LLC 2828 N Harwood Street, Suite 1220 Dallas, Texas 75201 United States of America Avidity Capital Partners Fund (GP) LP 2828 N Harwood Street, Suite 1220 Dallas, Texas 75201 United States of America Avidity Capital Partners (GP) LLC 2828 N Harwood Street, Suite 1220 Dallas, Texas 75201 United States of America Avidity Master Fund LP 2828 N Harwood Street, Suite 1220 Dallas, Texas 75201 United States of America Avidity Private Master Fund I LP 2828 N Harwood Street, Suite 1220 Dallas, Texas 75201 United States of America Michael Gregory c/o Avidity Partners Management LP 2828 N Harwood Street, Suite 1220 Dallas, Texas 75201 United States of America Avidity Partners Management LP - Delaware Avidity Partners Management (GP) LLC - Delaware Avidity Capital Partners Fund (GP) LP - Delaware Avidity Capital Partners (GP) LLC - Delaware Avidity Master Fund LP - Cayman Islands Avidity Private Master Fund I LP - Cayman Islands Michael Gregory - United States Y Avidity Partners Management LP - 4,426,565 Avidity Partners Management (GP) LLC - 4,426,565 Avidity Capital Partners Fund (GP) LP - 4,426,565 Avidity Capital Partners (GP) LLC - 4,426,565 Avidity Master Fund LP - 852,750 Avidity Private Master Fund I LP - 3,573,815 Michael Gregory - 4,426,565 Avidity Partners Management LP - 9.9% Avidity Partners Management (GP) LLC - 9.9% Avidity Capital Partners Fund (GP) LP - 9.9% Avidity Capital Partners (GP) LLC - 9.9% Avidity Master Fund LP - 2.0% Avidity Private Master Fund I LP - 8.1% Michael Gregory - 9.9% Avidity Partners Management LP - 0 Avidity Partners Management (GP) LLC - 0 Avidity Capital Partners Fund (GP) LP - 0 Avidity Capital Partners (GP) LLC - 0 Avidity Master Fund LP - 0 Avidity Private Master Fund I LP - 0 Michael Gregory - 0 Avidity Partners Management LP - 4,426,565 Avidity Partners Management (GP) LLC - 4,426,565 Avidity Capital Partners Fund (GP) LP - 4,426,565 Avidity Capital Partners (GP) LLC - 4,426,565 Avidity Master Fund LP - 852,750 Avidity Private Master Fund I LP - 3,573,815 Michael Gregory - 4,426,565 Avidity Partners Management LP - 0 Avidity Partners Management (GP) LLC - 0 Avidity Capital Partners Fund (GP) LP - 0 Avidity Capital Partners (GP) LLC - 0 Avidity Master Fund LP - 0 Avidity Private Master Fund I LP - 0 Michael Gregory - 0 Avidity Partners Management LP - 4,426,565 Avidity Partners Management (GP) LLC - 4,426,565 Avidity Capital Partners Fund (GP) LP - 4,426,565 Avidity Capital Partners (GP) LLC - 4,426,565 Avidity Master Fund LP - 852,750 Avidity Private Master Fund I LP - 3,573,815 Michael Gregory - 4,426,565 N Y N All of the securities reported in this Schedule 13G Amendment No. 8 are directly owned by advisory clients of Avidity Partners Management LP. None of those advisory clients, other than Avidity Private Master Fund I LP, may be deemed to beneficially own more than 5% of the Common Stock, par value $0.001 per share. N Please see Exhibit B attached hereto. Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. [Exhibit A - Joint Filing Agreement] [Exhibit B - Control Person Identification] Avidity Partners Management LP By: Avidity Partners Management (GP) LLC, its general partner, By: /s/ Michael Gregory Michael Gregory, Managing Member 02/17/2026 Avidity Partners Management (GP) LLC /s/ Michael Gregory Michael Gregory, Managing Member 02/17/2026 Avidity Capital Partners Fund (GP) LP By: Avidity Capital Partners (GP) LLC, its general, By: /s/ Michael Gregory Michael Gregory, Managing Member 02/17/2026 Avidity Capital Partners (GP) LLC By: Avidity Capital Partners (GP) LLC, its general partner, By: /s/ Michael Gregory Michael Gregory, Managing Member 02/17/2026 Avidity Master Fund LP By: Avidity Capital Partners Fund (GP) LP, its general partner, By: Avidity Capital Partners (GP) LLC, its general partner, By: /s/ Michael Gregory Michael Gregory, Managing Member 02/17/2026 Avidity Private Master Fund I LP By: Avidity Capital Partners Fund (GP) LP, its general partner, By: Avidity Capital Partners (GP) LLC, its general partner, By: /s/ Michael Gregory Michael Gregory, Managing Member 02/17/2026 Michael Gregory /s/ Michael Gregory Michael Gregory 02/17/2026 * Each Reporting Person disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein, and this report shall not be deemed an admission that such Reporting Person is the beneficial owner of the securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose. To the extent that "ownership of 5 percent or less of a class" was indicated in Item 5, such response only applies to the Reporting Person that indicated elsewhere herein that it beneficially owns five percent (5%) or less of the class.