X0508 4 2024-06-17 0001177648 ENANTA PHARMACEUTICALS INC ENTA 0001834835 Kieffer Tara Lynn C/O ENANTA PHARMACEUTICALS, INC. 500 ARSENAL STREET WATERTOWN MA 02472 0 1 0 0 Chief Product Strategy Officer 1 Common Stock 2024-06-17 4 S 0 7266 12.33 D 32341 D The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person in March 2024. The price reported in Column 4 is a weighted-average price. These shares were sold in multiple transactions at prices ranging from $12.20 to $12.54, inclusive. The reporting person undertakes to provide to Enanta Pharmaceuticals, Inc., any security holder of Enanta Pharmaceuticals, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in footnote 2 above. /s/ Paul J. Mellett as attorney-in-fact 2024-06-17