X0508 4 2024-02-12 0001177648 ENANTA PHARMACEUTICALS INC ENTA 0001942407 Rottinghaus Scott T. C/O ENANTA PHARMACEUTICALS, INC. 500 ARSENAL STREET WATERTOWN MA 02472 0 1 0 0 Chief Medical Officer 0 Common Stock 2024-02-12 4 A 0 2576 0 A 29042 D Common Stock 2024-02-12 4 F 0 755 12.41 D 28287 D Represents shares of Enanta common stock issued under performance share units ("PSUs") that vested as a result of performance against two-year research and development milestones in the calendar 2022-2023 period as determined by the Compensation Committee of Enanta's Board of Directors, and then settled with the issuance of the shares of Enanta common stock on February 12, 2024. Represents the number of shares of common stock automatically forfeited by the reporting person to cover withholding taxes due as a result of settlement of the PSU awards. /s/ Nathaniel S. Gardiner as attorney-in-fact 2024-02-14