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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
3 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Cash flows from operating activities    
Net loss $ (33,407) $ (28,986)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 8,099 7,139
Depreciation and amortization expense 642 511
Non cash interest expense associated with the sale of future royalties 299 0
Non-cash royalty revenue 487 0
Amortization (accretion) of premiums (discounts) on marketable securities 274 (339)
Change in operating assets and liabilities:    
Accounts receivable 441 (2,267)
Prepaid expenses and other current assets 18 (4,501)
Income tax receivable (730) 15
Operating lease, right-of-use assets 1,450 834
Other long-term assets 38 (5)
Accounts payable 5,174 (686)
Accrued expenses (6,736) (6,599)
Operating lease liabilities (1,023) (717)
Other long-term liabilities (14) (40)
Net cash used in operating activities (24,988) (35,641)
Cash flows from investing activities    
Purchase of marketable securities (146,845) (67,375)
Proceeds from maturities and sale of marketable securities 134,515 104,100
Purchase of property and equipment (787) (3,156)
Net cash provided by (used in) investing activities (13,117) 33,569
Cash flows from financing activities    
Payments on royalty sale liability, net of imputed interest (7,167) 0
Payments for settlement of share-based awards (183) (825)
Proceeds from exercise of stock options 0 1,126
Net cash provided by (used in) financing activities (7,350) 301
Net decrease in cash, cash equivalents and restricted cash (45,455) (1,771)
Cash, cash equivalents and restricted cash at beginning of period 89,356 47,962
Cash, cash equivalents and restricted cash at end of period 43,901 46,191
Supplemental disclosure of noncash information:    
Purchases of fixed assets included in accounts payable and accrued expenses 479 1,079
Operating lease liabilities arising from obtaining right-of-use assets 0 799
Supplemental disclosure of cash flow information    
Cash paid for interest $ 3,143 $ 0