CytoDyn Inc.

1111 Main Street, Suite 660

Vancouver, Washington 98660

February 13, 2019

VIA EDGAR SUBMISSION

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, NE

Washington, DC 20549

Re: REQUEST FOR ACCELERATION OF EFFECTIVENESS

CytoDyn Inc.

Registration Statement on Form S-3

File No. 333-228991

Ladies and Gentlemen:

CytoDyn Inc. (the “Company”) hereby respectfully requests the acceleration of the effectiveness of the above-referenced Registration Statement (the “Registration Statement”) so that the Registration Statement will become effective at 9:00 a.m. (Eastern time) on Thursday, February 14, 2019, or as soon thereafter as practicable.

Please notify James O’Grady of Lowenstein Sandler LLP, counsel to the Company, at (646) 414-6849 or jogrady@lowenstein.com, as soon as the Registration Statement has been declared effective.

Very truly yours,

CytoDyn Inc.

/s/ Michael D. Mulholland

Michael D. Mulholland

Chief Financial Officer