CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Cash flows from operating activities:
Net loss	$ (24,558,648)	$ (7,837,188)	$ (19,265,644)
Adjustments to reconcile net loss to net cash used by operating activities:
Non-cash compensation	2,183,317	1,193,949	1,173,743
Depreciation and amortization	731,578	660,788	581,532
Amortization of right of use asset	398,035
Bad debt expense (recovery)	(512)	(102,310)	72,429
Foreign currency transaction (gains) losses	2,577,913	(2,607,139)	350,365
Stock-based compensation	4,020,819	3,513,671	1,666,024
Amortization of loan acquisition costs		322,812	115,206
Changes in operating assets and liabilities:
Grants and accounts receivable	420,578	(326,860)	(642,171)
Inventories	(2,350,547)	(461,512)	(1,284,848)
Prepaid expenses and other current assets	280,915	(1,076,849)	(953,888)
Other assets	(135,857)	0	4,030
Accounts payable and accrued expenses	2,426,810	1,107,352	1,424,440
Net cash used by operating activities	(14,005,599)	(5,613,286)	(16,758,782)
Cash flows from investing activities:
Purchases of property and equipment	(3,641,248)	(708,395)	(698,165)
Patent costs	(640,013)	(967,823)	(821,952)
Net cash used by investing activities	(4,281,261)	(1,676,218)	(1,520,117)
Cash flows from financing activities:
Proceeds from long-term debt		1,410,900	5,000,000
Repayment of long-term debt		(16,410,900)	0
Final fee on long-term debt		(375,000)	0
Payment of loan acquisition costs		0	(4,212)
Equity contributions - net of fees incurred	(90,000)	80,214,008	673,653
Proceeds from exercise of stock options	805,199	1,509,322	739,747
Proceeds from exercise of warrants		0	1,768,491
Net cash provided by financing activities	715,199	66,348,330	8,177,679
Effect of exchange rates on cash	(24,774)	130,357	(35,199)
Net change in cash and cash equivalents	(17,596,435)	59,189,183	(10,136,419)
Cash and cash equivalents at beginning of year	71,421,601	12,232,418	22,368,837
Cash and cash equivalents at end of year	53,825,166	71,421,601	12,232,418
Supplemental disclosure of cash flow information:
Cash paid during the year for interest		1,127,647	1,059,541
Supplemental disclosure of non-cash financing activities:
Settlement of accrued bonuses with restricted stock units	$ 928,417	$ 657,780	$ 425,639