X0304 4 2011-09-07 0 0001175151 Cytosorbents Corp CTSO 0001368151 Capponi Vincent C/O CYTOSORBENTS CORP. 7 DEER PARK DRIVE, SUITE K MONMOUTH JUNCTION NJ 08852 0 1 0 0 Chief Operating Officer Common Stock 2011-09-07 2011-09-07 4 S 0 50000 0.27 D 7250000 D Stock Option 0.035 2011-09-07 2011-09-07 4 M 0 50000 D 2011-09-07 Common Stock 50000 7250000 D The shares of common stock were sold by Mr. Capponi pursuant to a 10b5-1 trading plan, adopted by the reporting person on June 14, 2011. In addition to the currently outstanding shares of common stock owned by Mr. Capponi and reported here, Mr. Capponi also beneficially owns the shares of common stock underlying the following stock options: options to purchase 50,000 shares of common stock at $1.65 per share; options to purchase 1,100,000 shares of common stock at $$0.25 per share; options to purchase 500,000 shares of common stock at $0.173 per share; options to purchase 400,000 shares of common stock at $0.168 per share; options to purchase 3,000,000 shares of common stock at $0.138 per share; and options to purchase 2,200,000 shares of common stock at $0.035 per share. N/A /s/ Vincent Capponi 2011-09-09