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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
3 Months Ended
Mar. 31, 2020
Mar. 31, 2019
Cash flows from operating activities:    
Net loss $ (3,452,779) $ (4,883,827)
Adjustments to reconcile net loss to net cash used by operating activities:    
Non-cash compensation 477,732 261,747
Depreciation and amortization 181,368 138,175
Amortization of debt costs 35,868 23,754
Bad debt 7,862 14,193
Stock-based compensation 729,429 227,658
Foreign currency transaction loss 668,488 393,455
Changes in operating assets and liabilities:    
Grants and accounts receivable (1,023,329) 611,668
Inventories 134,270 (395,683)
Prepaid expenses and other current assets 87,107 435,423
Accounts payable and accrued expenses (1,055,356) (1,064,124)
Net cash used by operating activities (3,209,340) (4,237,561)
Cash flows from investing activities:    
Purchases of property and equipment (235,551) (292,458)
Payments for patent costs (273,011) (181,769)
Net cash used by investing activities (508,562) (474,227)
Cash flows from financing activities:    
Equity contributions - net of fees incurred 17,743,226 0
Proceeds from exercise of stock options 138,430 236,070
Proceeds from exercise of warrants 0 1,768,491
Net cash provided by financing activities 17,881,656 2,004,561
Effect of exchange rates on cash (7,151) (14,236)
Net change in cash and cash equivalents 14,156,603 (2,721,463)
Cash and cash equivalents - beginning of period 12,232,418 22,368,837
Cash and cash equivalents - end of period 26,389,021 19,647,374
Supplemental disclosure of cash flow information:    
Cash paid during the period for interest 318,879 227,681
Supplemental disclosure of non-cash financing activities    
Settlement of accrued bonuses with restricted stock units 328,939 425,639
Equity contribution proceeds in transit $ 1,798,395 $ 0