-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 NDMwlrEz+ebfmk9Tf3xI824Ndu48Z9megsLpG3KCLdqAksj0VkmAGuWltWF86sbJ
 qgkOzOqmS3BydqI20BLkSQ==

<SEC-DOCUMENT>0001085037-08-000435.txt : 20080423
<SEC-HEADER>0001085037-08-000435.hdr.sgml : 20080423
<ACCEPTANCE-DATETIME>20080423133933
ACCESSION NUMBER:		0001085037-08-000435
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20080403
FILED AS OF DATE:		20080423
DATE AS OF CHANGE:		20080423

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			UPSTREAM BIOSCIENCES INC.
		CENTRAL INDEX KEY:			0001174891
		STANDARD INDUSTRIAL CLASSIFICATION:	IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
		IRS NUMBER:				980371433
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			0930

	BUSINESS ADDRESS:	
		STREET 1:		SUITE 200 - 1892 WEST BROADWAY
		CITY:			VANCOUVER
		STATE:			A1
		ZIP:			V6J 1Y9
		BUSINESS PHONE:		604-638-1674

	MAIL ADDRESS:	
		STREET 1:		SUITE 200 - 1892 WEST BROADWAY
		CITY:			VANCOUVER
		STATE:			A1
		ZIP:			V6J 1Y9

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	INTEGRATED BRAND SOLUTIONS INC
		DATE OF NAME CHANGE:	20020605

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			CAUWENBERGH GEERT
		CENTRAL INDEX KEY:			0001285648

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-50331
		FILM NUMBER:		08771339

	BUSINESS ADDRESS:	
		STREET 1:		1 STULTZ DR
		CITY:			PLAINSBORO
		STATE:			NJ
		ZIP:			08536
		BUSINESS PHONE:		6099451200

	MAIL ADDRESS:	
		STREET 1:		1 STULTS DRIVE
		CITY:			PLAINSBORO
		STATE:			NJ
		ZIP:			08536
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>f3geert_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2008-04-03</periodOfReport>

    <noSecuritiesOwned>1</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001174891</issuerCik>
        <issuerName>UPSTREAM BIOSCIENCES INC.</issuerName>
        <issuerTradingSymbol>UPBS</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001285648</rptOwnerCik>
            <rptOwnerName>CAUWENBERGH GEERT</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O BARRIER THERAPEUTICS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>600 COLLEGE RD EAST, STE 3200</rptOwnerStreet2>
            <rptOwnerCity>PRINCETON</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>08540</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <ownerSignature>
        <signatureName>/s/ Geert Cauwenberg</signatureName>
        <signatureDate>2008-04-03</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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