X0202 4 2006-03-01 0 0001174891 UPSTREAM BIOSCIENCES INC. UPBS 0001277156 BAJIC STEVE 806 - 699 CARDERO STREET VANCOUVER A1 V6G 3H7 BRITISH COLUMBIA, CANADA 1 1 0 0 Secretary and Treasurer Common shares 2006-03-01 4 I 0 31150000 0 D 2000000 D Mr. Bajic initially owned 1,105,000 common shares of the Issuer. The Issuer completed a 20 for 1 forward stock split on March 8, 2005 and a 1.5 for 1 forward stock split on December 20, 2005. As a result of the two stock splits, Mr. Bajic held 33,150,000 common shares. On March 1, 2006, Mr. Bajic tendered 31,150,000 common shares for cancellation without consideration. /s/ Steve Bajic 2006-03-10