X0306 4 2019-02-23 0000078003 PFIZER INC PFE 0001174449 CANGIALOSI LORETTA V PFIZER INC.-CORP. SECRETARY 235 EAST 42ND ST. NEW YORK NY 10017 1 Sr. Vice President, Controller Common Stock 2019-02-23 4 M 0 30864.0000 21.0300 A 115139.0000 D Common Stock 2019-02-23 4 F 0 7756.0000 42.9600 D 107383.0000 D Common Stock 2019-02-23 4 F 0 9610.0000 41.9100 D 97773.0000 D Common Stock 2019-02-25 4 F 0 1759.0000 43.0800 D 96014.0000 D Common Stock 2098.0000 I By Rule 16b-3 Plan Stock Appreciation Rights 21.0300 2019-02-23 4 M 0 30864.0000 0.0000 D 2019-02-23 2019-02-23 Common Stock 30864.0000 0.0000 D The reported transaction constitutes the earn-out of stock appreciation rights (including dividend equivalents thereon). The reported transaction constitutes the withholding of shares to satisfy tax obligations in connection with earn-out of stock appreciation rights. Price is the closing price of Pfizer common stock on February 22, 2019 The reported transaction constitutes the withholding of shares to cover payment of exercise price in connection with earn-out of stock appreciation rights (including dividend equivalents thereon). Under the terms of the settlement of the stock appreciation rights the 20-day average of the closing prices of Pfizer common stock ending on the settlement date is used. The reported transaction constitutes the withholding of shares to satisfy tax obligations upon the vesting of restricted stock units (including dividend equivalents thereon). Susan E. Grant, by power of atty., for Loretta V. Cangialosi 2019-02-26