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        <entityName>VAXINNATE CORP</entityName>
        <issuerAddress>
            <street1>Three Cedar Brook Drive</street1>
            <city>Cranbury</city>
            <stateOrCountry>NJ</stateOrCountry>
            <zipCode>08512</zipCode>
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        <entityType>Corporation</entityType>
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                <firstName>Andrew</firstName>
                <middleName>T.</middleName>
                <lastName>Drechsler</lastName>
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                <street1>Three Cedar Brook Drive</street1>
                <city>Cranbury</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>08512</zipCode>
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            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
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            <relationshipClarification>Chief Financial Officer and Secretary</relationshipClarification>
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                <lastName>Shaw</lastName>
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                <city>Cranbury</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>08512</zipCode>
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            <relationshipClarification>President and Chief Executive Officer</relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Franklin</firstName>
                <middleName>H.</middleName>
                <lastName>Top, Jr.</lastName>
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                <city>Cranbury</city>
                <stateOrCountry>NJ</stateOrCountry>
                <zipCode>08512</zipCode>
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                <firstName>Seth</firstName>
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                <lastName>Berkley</lastName>
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                <firstName>Philippe</firstName>
                <middleName></middleName>
                <lastName>Chambon</lastName>
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            <relatedPersonAddress>
                <street1>c/o New Leaf Ventures I, L.P.,</street1>
                <street2>7 Times Square, Suite 1603</street2>
                <city>New York</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10036</zipCode>
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                <lastName>Lawlor</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o HealthCare Ventures VII, L.P.</street1>
                <street2>44 Nassau Street</street2>
                <city>Princeton</city>
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                <zipCode>08542</zipCode>
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                <street1>c/o Canaan VII L.P.</street1>
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                <city>Rowayton</city>
                <stateOrCountry>CT</stateOrCountry>
                <zipCode>06853</zipCode>
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                <firstName>Gregory</firstName>
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                <lastName>Weinhoff</lastName>
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                <street1>c/o CHL Medical Partners II, L.P.</street1>
                <street2>1055 Washington Boulevard, 6th Floor</street2>
                <city>Stamford</city>
                <stateOrCountry>CT</stateOrCountry>
                <zipCode>06901</zipCode>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Julie</firstName>
                <middleName></middleName>
                <lastName>Eskay-Eagle</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>Wellcome Trust Investments 2 Unlimited</street1>
                <street2>215 Euston Road</street2>
                <city>London</city>
                <stateOrCountry>X0</stateOrCountry>
                <zipCode>NW12BE</zipCode>
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    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-05-05</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>3558</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>31000000</totalOfferingAmount>
            <totalAmountSold>15000000</totalAmountSold>
            <totalRemaining>16000000</totalRemaining>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>12</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
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                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
                <isEstimate>true</isEstimate>
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        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>VAXINNATE CORP</issuerName>
                <signatureName>/s/ Andrew T. Drechsler</signatureName>
                <nameOfSigner>Andrew T. Drechsler</nameOfSigner>
                <signatureTitle>Chief Financial Officer and Secretary</signatureTitle>
                <signatureDate>2009-05-18</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
