SEC Form 4

FORM 4		UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940	OMB APPROVAL OMB Number: 3235-0287 Estimated average burden hours per response: 0.5
X	Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person* Cosmo Technologies Ltd (Last) (First) (Middle) 42-43 AMIENS ST. (Street) DUBLIN, IRELAND L2 1 (City) (State) (Zip)	2. Issuer Name and Ticker or Trading Symbol SANTARUS INC [ SNTS ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director X 10% Owner Officer (give title below) Other (specify below)
	3. Date of Earliest Transaction (Month/Day/Year) 05/15/2013
	4. If Amendment, Date of Original Filed (Month/Day/Year)	6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	05/15/2013		S		4,887,500	D	$17.6751(1)	2,991,044	D(2)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

1. Name and Address of Reporting Person* Cosmo Technologies Ltd (Last) (First) (Middle) 42-43 AMIENS ST. (Street) DUBLIN, IRELAND L2 1 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Cipriano Giuseppe (Last) (First) (Middle) VIA C. COLOMBO, 1 (Street) LAINATE-MILANO, ITALY L6 20020 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director 10% Owner Officer (give title below) X Other (specify below) Related Entity

1. Name and Address of Reporting Person* Cosmo Holding S.p.A. (Last) (First) (Middle) PIAZZA DELLA REPUBBLICA, 3 (Street) MILANO, ITALY L6 20121 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director 10% Owner Officer (give title below) X Other (specify below) Related Entity

1. Name and Address of Reporting Person* Cosmo Pharmaceuticals S.p.A. (Last) (First) (Middle) VIA C. COLOMBO, 1 (Street) LAINATE-MILANO, ITALY L6 20020 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director 10% Owner Officer (give title below) X Other (specify below) Related Entity

1. Name and Address of Reporting Person* Ajani Mauro (Last) (First) (Middle) VIA C. COLOMBO, 1 (Street) LAINATE-MILANO, ITALY L6 20020 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director 10% Owner Officer (give title below) X Other (specify below) Related Entity

1. Name and Address of Reporting Person* Moro Luigi (Last) (First) (Middle) VIA C. COLOMBO, 1 (Street) LAINATE-MILANO, ITALY L6 20020 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director 10% Owner Officer (give title below) X Other (specify below) Related Entity

Explanation of Responses:

1. The complete price is $17.675125.

2. These securities are owned directly by Cosmo Technologies Ltd., which is a wholly-owned subsidiary of Cosmo Pharmaceuticals S.p.A., which is a majority owned subsidiary of Cosmo Holding S.p.A. Cosmo Pharmaceuticals S.p.A. and Cosmo Holding S.p.A. may be deemed indirect beneficial owners of the reported securities. Messrs. Giuseppe Cipriano, Luigi Moro and Mauro Ajani may also be deemed to be indirect beneficial owners of the reported securities due to their relationship with these entities.

	/s/ Cosmo Technologies Ltd., by Giuseppe Cipriano	05/15/2013
	/s/ Giuseppe Cipriano, Individually	05/15/2013
	/s/ Cosmo Holding S.p.A., by Mauro Ajani	05/15/2013
	/s/ Cosmo Pharmaceuticals S.p.A., by Mauro Ajani	05/15/2013
	/s/ Mauro Ajani, Individually	05/15/2013
	/s/ Luigi Moro, Individually	05/15/2013
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
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