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Note 1 - Basis of Presentation, Business and Organization (Details) (USD $)
Jun. 30, 2013
Dec. 31, 2012
Jun. 30, 2012
Dec. 31, 2011
Disclosure Text Block [Abstract]        
Common Stock, Par or Stated Value Per Share (in Dollars per share) $ 0.001 $ 0.001    
Patents Issued 2      
Patents Filed 93      
Retained Earnings (Accumulated Deficit) (in Dollars) $ (75,061,370) $ (71,313,550)    
Cash and Cash Equivalents, at Carrying Value (in Dollars) $ 53,408,680 $ 13,000,372 $ 4,630,449 $ 7,216,663