Stockholders' Deficit (Tables)

3 Months Ended

Mar. 31, 2022

Equity [Abstract]

Summary of Stock Based Compensation Recognized in Consolidated Statement of Operations

Stock-based compensation expense (including employee stock purchase plan expense) recorded in the accompanying condensed consolidated statements of operations for the three months ended March 31, 2022 and 2021 was as follows:

	Three Months Ended March 31,
	2022		2021
Selling, general and administrative	$	192,903	$	319,849
Research and development		66,904		23,234
Cost of product and product-related services revenue		7,998		7,856
	$	267,805	$	350,939

Summary of Stock Option Plans Activity Including Inducement Award Activity

A summary of the Company’s stock option activity (including inducement award activity) for the three months ended March 31, 2022 is as follows:

	Number of Shares			Weighted- Average Exercise Price Per Share		Weighted- Average Remaining Contractual Life (Years)		Aggregate Intrinsic Value
Balance at December 31, 2021		559,336		$	13.93		8.2	$	30,267
Granted		29,500			3.74
Exercised		-			-
Forfeited		(17,494	)		5.89
Expired/Cancelled		(33,876	)		34.94
Balance at March 31, 2022		537,466		$	12.31		8.2	$	-
Exercisable at March 31, 2022		283,983		$	17.79		7.4	$	-

Summary of Restricted Stock Unit ("RSU") Award Activity

The following table summarizes restricted stock unit (“RSU”) award activity for the three months ended March 31, 2022:

	Number of Shares			Weighted- Average Grant Date Fair Value Per Share
Balance at December 31, 2021		31,177		$	6.93
Granted		-			-
Released		(4,148	)		9.60
Forfeited		-			-
Balance at March 31, 2022		27,029			6.52
Vested and unissued at March 31, 2022		4,148		$	9.60