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Income Taxes - Difference in Actual Income Tax Expense Computed by Applying the Statutory Federal Income Tax Rate to Loss Before Income Taxes (Details) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Line Items]    
Computed tax (benefit) at 21% $ (3,586,925) $ (4,379,719)
State taxes, net of federal benefit (1,177,951) (832,055)
Stock-based compensation 240,177 310,811
Foreign tax rate differential (2,171) 3,685
Return to provision 53,340 26,120
Nontaxable loan forgiveness (360,570)  
Other 9,048 31,850
Uncertain tax position adjustment for prior periods (6,395) (5,694)
Increase in valuation allowance 5,331,692 5,276,244
Total income tax expense 22,475 14,415
State    
Income Tax Disclosure [Line Items]    
Research and development tax credit (265,362) (218,991)
Federal    
Income Tax Disclosure [Line Items]    
Research and development tax credit $ (212,408) $ (197,836)