Stockholders' Equity - Additional Information (Details)					1 Months Ended	12 Months Ended
	Nov. 20, 2020 $ / shares shares	Mar. 24, 2020 USD ($) $ / shares shares	Feb. 25, 2020 USD ($) $ / shares shares	Nov. 30, 2019 $ / shares	Nov. 30, 2020	Dec. 31, 2021 USD ($) $ / shares shares	Dec. 31, 2020 USD ($) $ / shares shares	Dec. 31, 2019 shares	Dec. 31, 2015 shares	Aug. 31, 2021 shares	Jul. 31, 2021 shares	Aug. 31, 2020 shares	Sep. 30, 2019 $ / shares shares
Class Of Stock [Line Items]
Reverse stock split, description						On November 20, 2020, the Company completed a reverse stock split of its outstanding shares of common stock pursuant to which every fifteen (15) shares of issued and outstanding common stock were exchanged for one share of its common stock.
Stock split conversion ratio	0.067
Common stock split Price per share | $ / shares	$ 4.27
Fractional shares from reverse stock split share	0
Common stock, shares outstanding						7,588,085	5,199,997
Common stock, shares issued						7,588,085	5,199,997
Common stock, shares authorized						26,666,667	26,666,667
Common stock, par value | $ / shares						$ 0.001	$ 0.001
Preferred stock, shares authorized						10,000,000
Preferred stock, par value | $ / shares						$ 0.001
Weighted-average fair value of stock options granted | $ / shares						$ 4.38	$ 6.40
Maximum aggregate number of common stock available purchase under employee stock purchase plan									16,666
Maximum number of shares that may be purchased by eligible participants under employee stock purchase plan									500
Stock issued under employee stock purchase plans						0	0
Employee Stock Option
Class Of Stock [Line Items]
Stock option granted						153,833	387,178
Unrecognized compensation expense | $						$ 1,300,000
Compensation expense period expected to be recognized						2 years 6 months 7 days
Options to purchase common stock outstanding						559,336	487,227	193,660
Restricted Stock Units R S U
Class Of Stock [Line Items]
Unrecognized compensation expense | $						$ 200,000
Compensation expense period expected to be recognized						1 year 5 months 19 days
Weighted-average fair value of RSUs granted | $ / shares						$ 5.20	$ 7.83
Vested and unissued RSU awards, description						Vested and unissued awards at December 31, 2021 represents RSU awards granted in August 2018 and November 2021 for which a portion of the awards vested on December 31, 2021, but for which issuance of shares occurred in  January 2022.
Vested and unissued RSU awards granted date						Aug. 31, 2018
Vested and unissued RSU awards vesting date						Dec. 31, 2021
Vested and unissued RSU awards issuance date						Jan. 31, 2022
Restricted Stock Units R S U | Share-based Payment Arrangement, Tranche One
Class Of Stock [Line Items]
Vested and unissued RSU awards granted date						Nov. 30, 2021
2020 Equity Incentive Plan
Class Of Stock [Line Items]
Shares reserved for issuance												744,685
Number of shares available for issuance						558,865
2014 Equity Incentive Plan
Class Of Stock [Line Items]
Shares reserved for issuance												68,552
Number of shares available for issuance												0
Options granted in term								10 years
2021 Inducement Plan
Class Of Stock [Line Items]
Shares reserved for issuance											300,000
Number of shares available for issuance											160,000
2021 Inducement Plan | Restricted Stock Units R S U
Class Of Stock [Line Items]
Stock option granted						30,000	0
Inducement Awards | Employee Stock Option
Class Of Stock [Line Items]
Stock option granted						110,000	0
Amended and Restated 2014 Employee Stock Purchase Plan
Class Of Stock [Line Items]
Shares reserved for issuance										500,000
2014 Employee Stock Purchase Plan
Class Of Stock [Line Items]
Shares reserved for issuance										24,285
Maximum | 2014 Equity Incentive Plan | Board Of Directors
Class Of Stock [Line Items]
Options exercise period								4 years
Minimum | 2014 Equity Incentive Plan | Board Of Directors
Class Of Stock [Line Items]
Options exercise period								1 year
Common Stock
Class Of Stock [Line Items]
Reverse stock split, description						In November 2020, the Company completed a reverse stock split of its outstanding shares of common stock pursuant to which every fifteen shares of issued and outstanding common stock were exchanged for one share of common stock.
Stock split conversion ratio					0.15
Number of shares issued upon the conversion						144,881	183,333
Stock issued under employee stock purchase plans						33,963	6,286
Cantor Sales Agreement
Class Of Stock [Line Items]
Common stock price per share | $ / shares				$ 0.001
Percentage of commission aggregate gross proceeds from each sale of shares				3.00%
Exchange Agreement
Class Of Stock [Line Items]
Common stock, shares outstanding			274,000
Conversion of convertible preferred stock into common stock			6.67
Exchange Agreement | Common Stock
Class Of Stock [Line Items]
Number of shares issued upon the conversion			27,500
Exchange Agreement | Series A Convertible Preferred Stock
Class Of Stock [Line Items]
Issuance of common stock, shares			10,170
Preferred stock, shares issued			41,100
Preferred stock, par value | $ / shares			$ 0.001
Issuance of common stock | $			$ 600,000
Stock issued, price per share | $ / shares			$ 59.00
Preferred stock, shares converted			183,333
Preferred stock, shares outstanding						23,770
L P Purchase Agreement
Class Of Stock [Line Items]
Issuance of common stock | $						$ 899,980
L P Purchase Agreement | Common Stock
Class Of Stock [Line Items]
Issuance of common stock, shares						154,372
Issuance of common stock | $						$ 154
Lincoln Park | L P Purchase Agreement
Class Of Stock [Line Items]
Common stock price per share | $ / shares		$ 5.2155
Net proceeds from issuance of common stock from the ATM Offering | $						$ 900,000	$ 1,000,000.0
Common stock value right to sell, maximum | $		$ 20,000,000.0
Agreement term		36 months
Minimum purchase amount extent to sell shares | $		$ 150,000
Maximum amount of any single business day's purchase shares		166,666
Percentage of common stock outstanding		19.99%
Percentage of beneficially owing common stock		9.99%
Common stock, shares issued		41,026				154,372	197,632
Common stock weighted average price per share | $ / shares						$ 5.83	$ 4.94
Lincoln Park | L P Purchase Agreement | Maximum
Class Of Stock [Line Items]
Number of common stock may sell in regular purchase on single business day		20,000
Lincoln Park | L P Purchase Agreement | Maximum | Closing Price of Common Stock is Not Below $7.50
Class Of Stock [Line Items]
Increased number of common stock may sell in regular purchase on single business day		23,333
Lincoln Park | L P Purchase Agreement | Maximum | Closing Price of Common Stock is Not Below $11.25
Class Of Stock [Line Items]
Increased number of common stock may sell in regular purchase on single business day		26,666
Lincoln Park | L P Purchase Agreement | Minimum
Class Of Stock [Line Items]
Closing stock price | $ / shares		$ 1.50
Lincoln Park | L P Purchase Agreement | Minimum | Closing Price of Common Stock is Not Below $7.50
Class Of Stock [Line Items]
Closing stock price of common stock | $ / shares		7.50
Lincoln Park | L P Purchase Agreement | Minimum | Closing Price of Common Stock is Not Below $11.25
Class Of Stock [Line Items]
Closing stock price of common stock | $ / shares		$ 11.25
Private Placement | Institutional Accredited Investors
Class Of Stock [Line Items]
Exercise price of warrants | $ / shares													$ 9.75
Private Placement | Institutional Accredited Investors | Pre-funded Warrants
Class Of Stock [Line Items]
Number of securities called by warrants													360,779
Exercise price of warrants | $ / shares													$ 9.60
Exercise price of warrants, exercisable subject to beneficial ownership limitations | $ / shares													$ 0.15
ATM Offering
Class Of Stock [Line Items]
Gross proceeds from issuance of common stock | $						$ 11,000,000.0	$ 7,900,000
Payment of sales commissions | $						300,000	200,000
Net proceeds from issuance of common stock from the ATM Offering | $						10,700,000	7,500,000
Issuance of common stock | $						$ 10,665,819	$ 7,545,838
ATM Offering | Common Stock
Class Of Stock [Line Items]
Issuance of common stock, shares						2,050,879	955,240
Deferred offering costs | $							$ 100,000
Issuance of common stock | $						$ 2,051	$ 955
ATM Offering | Common Stock
Class Of Stock [Line Items]
Issuance of common stock, shares						2,050,879
Employee Stock Purchase Plan
Class Of Stock [Line Items]
Shares reserved for issuance						503,959
Number of shares available for issuance							11,658
Vested and unissued RSU awards, description						Under the 2014 ESPP, the number of shares of common stock reserved for issuance automatically increased on January 1 of each calendar year, from January 1, 2016 to January 1, 2021 by the lesser of (i) 1% of the total number of shares of the Company’s common stock outstanding on December 31 of the preceding calendar year, (ii) 13,000 shares, or (iii) a number determined by the Company’s Board of Directors that is less than (i) and (ii).
Common stock issuance offering date						Jan. 01, 2016
Common stock issuance expiration date						Jan. 01, 2021
Percentage of common stock outstanding						1.00%
Options to purchase common stock outstanding						13,000
Maximum contribution eligible compensation during a period to purchase common stock						15.00%
Fair market value of company common stock, shares offering price						85.00%
Fair market value of company common stock, shares purchase price						85.00%