Stockholders Deficit (Tables)

9 Months Ended

Sep. 30, 2021

Equity [Abstract]

Summary of Stock Based Compensation Recognized in Consolidated Statement of Operations

Stock-based compensation expense (including employee stock purchase plan expense) recorded in the accompanying condensed consolidated statements of operations for the three and nine months ended September 30, 2021 and 2020 was as follows:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2021		2020		2021		2020
Selling, general and administrative	$	293,916	$	383,679	$	934,446	$	1,079,754
Research and development		35,566		2,044		83,108		85,462
Cost of product and product-related services revenue		9,411		6,440		24,764		14,498
	$	338,893	$	392,163	$	1,042,318	$	1,179,714

Summary of Stock Option Plans Activity

A summary of the Company’s stock option activity for the nine months ended September 30, 2021 is as follows:

	Number of Shares			Weighted- Average Exercise Price Per Share		Weighted- Average Remaining Contractual Life (Years)		Aggregate Intrinsic Value
Balance at December 31, 2020		487,227		$	16.78		8.6	$	1,536
Granted		70,333			5.74
Exercised		(75	)		4.35			$	107
Forfeited		(45,006	)		12.76
Expired/Cancelled		(18,229	)		25.64
Balance at September 30, 2021		494,250		$	15.25		8.2	$	19,222
Exercisable at September 30, 2021		283,107		$	20.65		7.6	$	5,882

Summary of Restricted Stock Unit ("RSU") Award Activity

The following table summarizes restricted stock unit (“RSU”) award activity for the nine months ended September 30, 2021:

	Number of Shares			Weighted- Average Grant Date Fair Value Per Share
Balance at December 31, 2020		12,214		$	28.61
Released		(3,540	)		29.96
Forfeited		(2,373	)		51.00
Balance at September 30, 2021		6,301		$	19.40
Vested and unissued at September 30, 2021		989		$	26.14