Stockholders Deficit (Tables)

6 Months Ended

Jun. 30, 2021

Equity [Abstract]

Summary of Stock Based Compensation Recognized in Consolidated Statement of Operations

Stock-based compensation expense recorded in the accompanying condensed consolidated statements of operations for the three and six months ended June 30, 2021 and 2020 was as follows:

	Three Months Ended June 30,				Six Months Ended June 30,
	2021		2020		2021		2020
Selling, general and administrative	$	320,681	$	338,063	$	640,530	$	696,075
Research and development		24,308		24,913		47,542		83,418
Cost of product and product-related services revenue		7,497		3,904		15,353		8,058
	$	352,486	$	366,880	$	703,425	$	787,551

Summary of Stock Option Plans Activity

A summary of the Company’s stock option activity for the six months ended June 30, 2021 is as follows:

	Number of Shares			Weighted- Average Exercise Price Per Share		Weighted- Average Remaining Contractual Life (Years)		Aggregate Intrinsic Value
Balance at December 31, 2020		487,227		$	16.78		8.6	$	1,536
Granted		7,833			4.15
Exercised		(75	)		4.35			$	107
Forfeited		(33,092	)		14.50
Expired/Cancelled		(16,303	)		27.51
Balance at June 30, 2021		445,590		$	16.33		8.3	$	17,079
Exercisable at June 30, 2021		231,587		$	23.13		7.5	$	4,020

Summary of Restricted Stock Unit ("RSU") Award Activity

The following table summarizes restricted stock unit (“RSU”) award activity for the six months ended June 30, 2021:

	Number of Shares			Weighted- Average Grant Date Fair Value Per Share
Balance at December 31, 2020		12,214		$	28.61
Released		(2,382	)		30.25
Forfeited		(2,373	)		51.00
Balance at June 30, 2021		7,459		$	20.95
Vested and unissued at June 30, 2021		1,158		$	29.36