Stockholders Deficit (Tables)

3 Months Ended

Mar. 31, 2021

Summary of Stock Based Compensation Recognized in Consolidated Statement of Operations

Stock-based compensation expense recorded in the accompanying condensed consolidated statements of operations for the three months ended March 31, 2021 and 2020 was as follows:

	Three Months Ended March 31,
	2021		2020
Selling, general and administrative	$	319,849	$	358,012
Research and development		23,234		58,505
Cost of product and product-related services revenue		7,856		4,154
	$	350,939	$	420,671

Equity Incentive Plans

Summary of Stock Option Plans Activity

A summary of the Company’s stock option activity for the three months ended March 31, 2021 is as follows:

	Number of Shares			Weighted- Average Exercise Price Per Share		Weighted- Average Remaining Contractual Life (Years)		Aggregate Intrinsic Value
Balance at December 31, 2020		487,227		$	16.78		8.6	$	1,536
Granted		333			5.99
Exercised		(75	)		4.35			$	107
Forfeited		(30,492	)		15.19
Expired/Cancelled		(3,498	)		27.02
Balance at March 31, 2021		453,495		$	16.80		8.4	$	3,740
Exercisable at March 31, 2021		213,614		$	24.99		7.5	$	1,179

Summary of Restricted Stock Unit ("RSU") Award Activity

The following table summarizes restricted stock unit (“RSU”) award activity for the three months ended March 31, 2021:

	Number of Shares			Weighted- Average Grant Date Fair Value Per Share
Balance at December 31, 2020		12,214		$	28.61
Released		(1,390	)		33.21
Forfeited		(2,373	)		51.00
Balance at March 31, 2021		8,451		$	21.55
Vested and unissued at March 31, 2021		992		$	26.11