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Condensed Consolidated Statements of Cash Flows - USD ($)
3 Months Ended
Mar. 31, 2020
Mar. 31, 2019
Operating activities    
Net loss $ (5,457,898) $ (5,370,846)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 348,633 308,984
Accretion of discount on NuvoGen obligation (3,430) (3,414)
Provision for excess inventory 6,947 24,296
Amortization of QNAH Convertible Note issuance costs 3,364 3,364
Amortization of MidCap Credit Facility discount and issuance costs 42,441 39,143
Stock-based compensation expense 415,292 241,246
Employee stock purchase plan expense 5,379 16,794
Amortization of operating lease right-of-use assets 151,726 72,923
Accrued interest on available-for-sale securities investments (74,101) (72,698)
Loss on abandonment of assets 49,226  
Changes in operating assets and liabilities:    
Accounts receivable 1,961,707 1,662,828
Inventory (375,178) 103,272
Prepaid expenses and other 139,508 9,777
Deferred offering costs 140,320  
Accounts payable (410,806) (480,546)
Accrued liabilities (668,667) (1,977,373)
Contract liabilities (18,794) (55,246)
Operating lease liabilities (186,220) (115,440)
Net cash used in operating activities (3,930,551) (5,592,936)
Investing activities    
Purchase of property and equipment (25,231) (103,316)
Sales, redemptions and maturities of available-for-sale securities 8,250,000 12,800,000
Purchase of available-for-sale securities (4,272,298) (8,099,573)
Net cash provided by investing activities 3,952,471 4,597,111
Financing activities    
Proceeds from ATM Offering, net 2,435,912  
Proceeds from Series A convertible preferred stock in private placement 600,030  
Proceeds from exercise of pre-funded warrants 31,768  
Payments on NuvoGen obligation (287,997) (463,686)
Payments on financing leases (11,833) (13,782)
Proceeds from exercise of stock options   51,570
Taxes paid for net share settlement of restricted stock awards (7,052) (9,685)
Payment of deferred offering costs   (30,175)
Net cash provided by (used in) financing activities 2,760,828 (465,758)
Effect of exchange rates on cash 1,201 4,063
Increase (decrease) in cash, cash equivalents and restricted cash 2,783,949 (1,457,520)
Cash, cash equivalents and restricted cash at beginning of period 10,889,995 11,702,847
Cash, cash equivalents and restricted cash at end of period 13,673,944 10,245,327
Supplemental disclosure of noncash investing and financing activities    
Fixed asset purchases payable and accrued at period end 289,838 13,945
Adoption of ASC 842, Leases   694,352
Deferred offering costs payable and accrued at period end   108,883
Issuance of Series A convertible preferred stock in exchange for outstanding common stock 2,424,900  
Series A convertible preferred stock in private placement, costs payable and accrued at period end 37,075  
Issuance of common stock in connection with LP Purchase Agreement 615  
LP Purchase Agreement, costs payable and accrued at period end 96,000  
Supplemental cash flow information    
Cash paid for interest $ 164,005 $ 172,032