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Stockholders Deficit - Summary of Stock-Based Compensation (Details) - USD ($)
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]    
Stock-based compensation $ 241,246 $ 1,143,458
Selling, General and Administrative    
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]    
Stock-based compensation 181,981 1,101,992
Research and Development    
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]    
Stock-based compensation 48,450 30,909
Cost of Product and Product-related Services Revenue    
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]    
Stock-based compensation $ 10,815 $ 10,557