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Condensed Statements of Cash Flows - USD ($)
9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Operating activities    
Net loss $ (14,326,084) $ (17,038,022)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 1,126,230 893,334
Accretion of discount on NuvoGen obligation (9,125) 147,753
Provision for excess inventory 63,840 302,085
Amortization of Growth Term Loan discount and issuance costs 62,951 325,517
Loss on extinguishment of Growth Term Loan 105,064  
Amortization of QNAH Convertible Note issuance costs 10,090  
Amortization of MidCap Credit Facility discount and issuance costs 92,060  
Stock-based compensation expense 1,643,353 1,171,988
Employee stock purchase plan expense 43,932 44,170
Accretion of incentive from landlord (106,500) (106,500)
Accrued interest on available-for-sale securities investments (292,308) 5,991
Other operating adjustments   1,307
Changes in operating assets and liabilities:    
Accounts receivable 2,994,935 (1,781,782)
Inventory 24,986 13,944
Prepaid expenses and other (245,488) (94,295)
Deferred offering costs 2,953 49,630
Accounts payable (123,266) 1,521,391
Accrued liabilities (1,216,171) 327,284
Contract liabilities (449,911) 469,276
Net cash used in operating activities (10,598,459) (13,746,929)
Investing activities    
Purchase of property and equipment (857,899) (525,437)
Sales, redemptions and maturities of available-for-sale securities 15,800,000 4,300,000
Purchase of available-for-sale securities (43,129,605)  
Net cash (used in) provided by investing activities (28,187,504) 3,774,563
Financing activities    
Proceeds from MidCap Credit Facility 7,000,000  
MidCap Credit Facility lender fees (422,390)  
Payments on Growth Term Loan (1,684,626) (4,740,774)
Payments for extinguishment of Growth Term Loan (4,276,988)  
Proceeds from public offering, net 37,932,290  
Public offering costs (207,974) (231,475)
Proceeds from ATM Offering, net 556,706 16,891,193
Payments on NuvoGen obligation (729,739) (600,000)
Payments on capital leases (59,186) (43,813)
Proceeds from exercise of stock options 204,173 165,261
Taxes paid for net share settlement of restricted stock awards (133,513)  
Proceeds from shares purchased under stock purchase plans 72,862 71,716
Net cash provided by financing activities 38,251,615 11,512,108
(Decrease) increase in cash, cash equivalents and restricted cash (534,348) 1,539,742
Cash and cash equivalents at beginning of period 9,968,600 7,507,659
Cash, cash equivalents and restricted cash at end of period 9,434,252 9,047,401
Supplemental disclosure of noncash investing and financing activities    
Fixed asset purchases payable and accrued at period end 29,615 410,184
Carrying value of demonstration units transferred from property and equipment to inventory 49,245 55,739
Equipment purchased through capital lease 63,809  
MidCap Term Loan fees and warrant discount 389,000  
Retirement of treasury stock   75,000
Supplemental cash flow information    
Cash paid for interest 369,360 575,480
Cash paid for taxes $ 3,545 $ 1,023