Condensed Statements of Changes in Stockholders' Equity (Deficit) - 9 months ended Sep. 30, 2018 - USD ($)	Total	ATM Offering	Underwritten Public Offering	Common Stock	Common Stock ATM Offering	Common Stock Underwritten Public Offering	Additional Paid-In Capital	Additional Paid-In Capital ATM Offering	Additional Paid-In Capital Underwritten Public Offering	Accumulated Other Comprehensive Loss	Accumulated Deficit
Balance at Dec. 31, 2017	$ (3,059,537)			$ 13,929			$ 131,492,595				$ (134,566,061)
Balance, shares at Dec. 31, 2017				13,929,763
Exercise of stock options	204,173			$ 96			204,077
Exercise of stock options, shares				96,164
Stock-based compensation expense	1,643,083						1,643,083
Release of restricted stock awards	270			$ 270
Release of restricted stock awards, shares				269,551
Net share settlement of restricted stock awards	(133,513)			$ (35)			(133,478)
Net share settlement of restricted stock awards, shares				(34,769)
Stock issued under stock purchase plans	116,794			$ 42			116,752
Stock issued under stock purchase plans, shares				42,280
Issuance of common stock		$ 556,706	$ 37,724,316		$ 262	$ 13,915		$ 556,444	$ 37,710,401
Issuance of common stock, shares					261,352	13,915,000
MidCap Term Loan warrant discount	74,000						74,000
Net loss	(14,326,084)										(14,326,084)
Other comprehensive loss	(8,882)									$ (8,882)
Balance at Sep. 30, 2018	$ 22,791,326			$ 28,479			$ 171,663,874			$ (8,882)	$ (148,892,145)
Balance, shares at Sep. 30, 2018				28,479,341