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Condensed Statements of Cash Flows - USD ($)
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Dec. 31, 2017
Operating activities          
Net loss     $ (9,482,676) $ (11,657,176)  
Adjustments to reconcile net loss to net cash used in operating activities:          
Depreciation and amortization $ 422,140 $ 291,421 778,344 587,466  
Accretion of discount on NuvoGen obligation     (6,006) 99,377  
Provision for excess inventory 12,253 51,599 23,533 244,026  
Amortization of Growth Term Loan discount and issuance costs     62,951 231,319  
Loss on extinguishment of Growth Term Loan     105,064    
Amortization of QNAH Convertible Note issuance costs     6,727    
Amortization of MidCap Credit Facility discount and issuance costs     48,092    
Stock-based compensation expense     1,385,378 814,583  
Employee stock purchase plan expense     28,906 29,223  
Accretion of incentive from landlord     (71,000) (71,000)  
Accrued interest on available-for-sale securities investments     (187,946) 5,991  
Changes in operating assets and liabilities:          
Accounts receivable     2,874,274 (173,427)  
Inventory     191,836 (19,673)  
Prepaid expenses and other     (402,102) (35,103)  
Deferred offering costs     2,953 49,630  
Accounts payable     (656,645) 480,025  
Accrued liabilities     (1,319,010) (456,675)  
Contract liabilities     (389,172) 278,310  
Net cash used in operating activities     (7,006,499) (9,593,104)  
Investing activities          
Purchase of property and equipment     (829,186) (152,339)  
Sales, redemptions and maturities of available-for-sale securities     3,300,000 4,300,000  
Purchase of available-for-sale securities     (38,079,329)    
Net cash (used in) provided by investing activities     (35,608,515) 4,147,661  
Financing activities          
Proceeds from MidCap Credit Facility     7,000,000    
MidCap Credit Facility lender fees     (422,390)    
Payments on Growth Term Loan     (1,684,626) (3,126,629)  
Payments for extinguishment of Growth Term Loan     (4,276,988)    
Proceeds from public offering, net     37,932,290    
Public offering costs     (207,974)    
Proceeds from ATM Offering, net     556,706 14,705,770  
Payments on NuvoGen obligation     (435,093) (400,000)  
Payments on capital leases     (40,017) (24,796)  
Proceeds from exercise of stock options     69,513 109,786  
Taxes paid for net share settlement of restricted stock awards     (133,513)    
Proceeds from shares purchased under the stock purchase plan     62,862 71,689  
Net cash provided by financing activities     38,420,770 11,335,820  
Increase (decrease) in cash and cash equivalents     (4,194,244) 5,890,377  
Cash and cash equivalents at beginning of period     9,968,600 7,507,659 $ 7,507,659
Cash and cash equivalents at end of period $ 5,774,356 $ 13,398,036 5,774,356 13,398,036 $ 9,968,600
Noncash investing and financing activities          
Fixed asset purchases payable and accrued at period end     2,730 72,224  
Deferred offering costs payable and accrued at period end       30,000  
Carrying value of demonstration units transferred from property and equipment to inventory     49,245 26,807  
Equipment purchased through capital lease     45,896    
MidCap Term Loan fees and warrant discount     389,000    
Retirement of treasury stock       75,000  
Supplemental cash flow information          
Cash paid for interest     202,573 417,782  
Cash paid for taxes     $ 3,545 $ 280