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Condensed Statements of Cash Flows - USD ($)
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Operating activities    
Net loss $ (5,379,947) $ (5,816,274)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 356,204 296,045
Accretion of discount on NuvoGen obligation (2,952) 50,124
Provision for excess inventory 11,280 192,427
Amortization of Growth Term Loan discount and issuance costs 62,951 122,583
Loss on extinguishment of Growth Term Loan 105,064  
Amortization of QNAH Convertible Note issuance costs 3,363  
Amortization of MidCap Credit Facility discount and issuance costs 2,924  
Stock-based compensation expense 1,143,458 396,646
Employee stock purchase plan expense 14,453 14,888
Accretion of incentive from landlord (35,500) (35,500)
Accrued interest on available-for-sale securities investments (66,195) (5,573)
Changes in operating assets and liabilities:    
Accounts receivable 3,351,907 181,312
Inventory 127,224 63,198
Prepaid expenses and other (21,494) 64,765
Deferred offering costs 2,953 10,830
Accounts payable (78,239) 311,036
Accrued liabilities (2,065,603) (388,339)
Contract liabilities (233,078) (93,874)
Net cash used in operating activities (2,701,227) (4,635,706)
Investing activities    
Purchase of property and equipment (457,828) (65,385)
Sales, redemptions and maturities of available-for-sale securities   1,700,000
Purchase of available-for-sale securities (25,070,165)  
Net cash (used in) provided by investing activities (25,527,993) 1,634,615
Financing activities    
Proceeds from MidCap Credit Facility 7,000,000  
MidCap Credit Facility lender fees (228,459)  
Payments on Growth Term Loan (1,684,626) (1,546,612)
Payments for extinguishment of Growth Term Loan (4,276,988)  
Proceeds from public offering, net 37,932,290  
Public offering costs (207,974)  
Proceeds from ATM Offering, net 556,706  
Payments on NuvoGen obligation (185,574) (200,000)
Payments on capital leases (20,786) (27,199)
Proceeds from exercise of stock options 40,504 35,023
Taxes paid for net share settlement of restricted stock awards (133,513)  
Net cash provided by (used in) financing activities 38,791,580 (1,738,788)
Increase (decrease) in cash and cash equivalents 10,562,360 (4,739,879)
Cash and cash equivalents at beginning of period 9,968,600 7,507,659
Cash and cash equivalents at end of period 20,530,960 2,767,780
Noncash investing and financing activities    
Fixed asset purchases payable and accrued at period end 3,486 44,256
Deferred offering costs payable and accrued at period end   76,262
Equipment purchased through capital lease 31,340  
Debt issuance costs payable and accrued at period end 193,931  
MidCap Term Loan fees and warrant discount 389,000  
Retirement of treasury stock   75,000
Supplemental cash flow information    
Cash paid for interest $ 83,397 225,713
Cash paid for taxes   $ 280