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Condensed Statements of Cash Flows - USD ($)
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Operating activities    
Net loss $ (5,816,274) $ (7,026,424)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 296,045 357,023
Accretion of discount on NuvoGen obligation 50,124 52,082
Provision for excess inventory 192,427 30,542
Amortization of Growth Term Loan discount and issuance costs 122,583 102,979
Stock-based compensation expense 396,646 170,048
Employee stock purchase plan expense 14,888  
Accretion of incentive from landlord (35,500) (23,666)
Accrued interest on available-for-sale securities investments (5,573) (7,288)
Changes in operating assets and liabilities:    
Accounts receivable 181,312 141,680
Inventory 63,198 (195,203)
Prepaid expenses and other 64,765 119,538
Deferred offering costs 10,830  
Accounts payable 311,036 714,361
Accrued liabilities (388,339) (537,061)
Deferred revenue (93,874) (22,028)
Net cash used in operating activities (4,635,706) (6,123,417)
Investing activities    
Purchase of property and equipment (65,385) (220,570)
Sales, redemptions and maturities of available-for-sale securities 1,700,000 3,000,000
Net cash provided by investing activities 1,634,615 2,779,430
Financing activities    
Proceeds from Growth Term Loan   5,000,000
Payments on Growth Term Loan 1,546,612  
Payments on capital leases 27,199 27,300
Proceeds from exercise of stock options 35,023  
Payments on NuvoGen obligation 200,000  
Net cash provided by (used in) financing activities (1,738,788) 4,972,700
Increase (decrease) in cash and cash equivalents (4,739,879) 1,628,713
Cash and cash equivalents at beginning of period 7,507,659 3,293,983
Cash and cash equivalents at end of period 2,767,780 4,922,696
Noncash investing and financing activities    
Allocation of term loan B warrant discount   122,460
Fixed asset purchases payable and accrued at period end 44,256 1,030,174
Deferred offering costs payable and accrued at period end 76,262  
Stock issued for settlement of accrued bonus   (364,910)
Purchase of property and equipment under capital lease   176,360
Incentive from landlord   710,000
Retirement of treasury stock 75,000  
Supplemental cash flow information    
Cash paid for interest $ 225,713 $ 237,397