Net Loss Per Share (Tables)

12 Months Ended

Dec. 31, 2016

Reconciliation of Numerator and Denominator Used in Computing Basic and Diluted Net Loss per Share

The following table provides a reconciliation of the numerator and denominator used in computing basic and diluted net loss per share for the periods presented:

	Years Ended December 31,
	2016			2015
Numerator:
Net loss	$	(26,039,550	)	$	(21,397,791	)
Accretion of stock issuance costs		—			(35,046	)
Accretion of discount on Series E warrants		—			(127,616	)
Series D and E Convertible Preferred Stock dividends		—			(1,165,932	)
Net loss attributable to common stockholders	$	(26,039,550	)	$	(22,726,385	)
Denominator:
Weighted-average common shares outstanding-basic and diluted		7,113,075			4,518,499
Net loss per share attributable to common stockholders, basic and diluted	$	(3.66	)	$	(5.03	)

Outstanding Options, Warrants and Restricted Stock Units Excluded from Computation of Diluted Net Loss per Share

The following outstanding options, warrants and restricted stock units were excluded from the computation of diluted net loss per share for the periods presented because their effect would have been anti-dilutive:

	Years Ended December 31,
	2016		2015
Options to purchase common stock		1,161,705		736,645
Common stock warrant		219,723		169,099
Restricted stock units		355,499		27,500