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Condensed Statements of Cash Flows - USD ($)
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Operating activities    
Net loss $ (7,026,424) $ (4,088,134)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 357,023 151,493
Accretion of discount on NuvoGen obligation 52,082 126,566
Bad debt expense, net of recoveries   (16,146)
Provision for excess inventory 30,542 21,926
Amortization of deferred financing costs 7,431 3,508
Amortization of discount on term loan 51,908 36,520
Amortization of final payment premium on term loan 43,640 24,237
Amortization of discount on convertible notes   32,006
Stock-based compensation expense 170,048 76,548
Change in redeemable convertible preferred stock warrant liability   (388,960)
Amortization of convertible note financing costs   15,107
Accretion of incentive from landlord (23,666)  
Accrued interest on available-for-sale securities investments (7,288)  
Loss on disposal of assets   49,341
Changes in operating assets and liabilities:    
Accounts receivable 141,680 (35,014)
Inventory (195,203) (431,598)
Prepaid expenses and other 119,538 (10,114)
Accounts payable 714,361 (69,456)
Accrued liabilities (537,061) 96,544
Deferred revenue (22,028) (9,233)
Net cash used in operating activities (6,123,417) (4,414,859)
Investing activities    
Purchase of property and equipment (220,570) (343,703)
Sales, redemptions and maturities of available-for-sale securities 3,000,000  
Net cash provided by (used in) investing activities 2,779,430 (343,703)
Financing activities    
Proceeds from exercise of stock options   4,972
Proceeds from exercise of E warrants   7,196
Deferred offering costs   (219,908)
Deferred convertible note financing costs   (75,535)
Payments on capital leases (27,300) (7,311)
Proceeds from term loan 5,000,000  
Proceeds from issuance of convertible note warrants   3,000,000
Net cash provided by financing activities 4,972,700 2,709,414
Increase (decrease) in cash and cash equivalents 1,628,713 (2,049,148)
Cash and cash equivalents at beginning of period 3,293,983 3,613,392
Cash and cash equivalents at end of period 4,922,696 1,564,244
Noncash investing and financing activities    
Accretion of preferred stock issuance costs   24,077
Accretion of dividends   798,582
Accrual of deferred offering and finance costs   96,598
Allocation of Series E warrant convertible notes debt discount   741,828
Allocation of term loan B warrant discount 122,460  
Fixed asset purchases payable and accrued for payment at period end 1,030,174  
Stock issued for payment of 2015 annual bonus (364,910)  
Purchase of property and equipment under capital lease 176,360  
Incentive from landlord 710,000  
Supplemental cash flow information    
Cash paid for interest $ 237,397 233,750
Series D And E Redeemable Convertible Preferred Stock    
Noncash investing and financing activities    
Accretion of dividends   798,582
Series E Warrants    
Noncash investing and financing activities    
Exercise of warrants   (4,116)
Accretion of warrant discount   $ 87,470