Net Loss Per Share (Tables)

3 Months Ended

Mar. 31, 2016

Reconciliation of Numerator and Denominator Used in Computing Basic and Diluted Net Loss per Share

The following table provides a reconciliation of the numerator and denominator used in computing basic and diluted net loss per share for the periods presented:

	Three Months Ended March 31,
	2016			2015
Numerator:
Net loss	$	(7,026,424	)	$	(4,088,134	)
Accretion of stock issuance costs		—			(24,077	)
Accretion of discount on Series E warrants		—			(87,470	)
Series E and D, Convertible Preferred Stock dividends		—			(798,582	)
Net loss attributable to common stockholders	$	(7,026,424	)	$	(4,998,263	)
Denominator:
Weighted-average common shares outstanding-basic and diluted		6,885,522			333,408
Net loss per share attributable to common stockholders, basic and diluted	$	(1.02	)	$	(14.99	)

Outstanding Options, Warrants and Convertible Preferred Stock Excluded from Computation of Diluted Net Loss per Share

The following outstanding options, warrants and convertible preferred stock were excluded from the computation of diluted net loss per share for the periods presented because their effect would have been anti-dilutive:

	Three Months Ended March 31,
	2016		2015
Options to purchase common stock		1,045,060		593,663
Convertible Preferred Stock (as converted)		—		2,127,463
Convertible Preferred Stock warrants (as converted)		—		136,908
Common stock warrant		219,723		931