Net Loss Per Share (Tables)

12 Months Ended

Dec. 31, 2015

Reconciliation of Numerator and Denominator Used in Computing Basic and Diluted Net Loss per Share

The following table provides a reconciliation of the numerator and denominator used in computing basic and diluted net loss per share for the periods presented:

	December 31,
	2015			2014
Numerator:
Net loss	$	(21,397,791	)	$	(13,958,408	)
Accretion of stock issuance costs		(35,046	)		(102,677	)
Accretion of Series E warrant discount		(127,616	)		(313,152	)
Accretion of Series D and E Redeemable Convertible Preferred Stock dividends		(1,165,932	)		(3,244,572	)
Net loss attributable to common stockholders	$	(22,726,385	)	$	(17,618,809	)
Denominator:
Weighted-average common shares outstanding-basic and diluted		4,518,499			100,659
Net loss per share attributable to common stockholders, basic and diluted	$	(5.03	)	$	(175.03	)

Outstanding Options, Warrants and Convertible Preferred Stock Excluded from Computation of Diluted Net Loss per Share

The following outstanding options, warrants and Convertible Preferred Stock were excluded from the computation of diluted net loss per share for the periods presented because their effect would have been anti-dilutive:

	Years Ended December 31,
	2015		2014
Options to purchase common stock		736,645		595,577
Restricted stock units		27,500		—
Convertible Preferred Stock (as converted)		—		2,126,982
Convertible Preferred Stock warrants (as converted)		—		50,681
Common stock warrant		169,099		931