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Stockholders' Deficit (Tables)
3 Months Ended
Mar. 31, 2023
Equity [Abstract]  
Summary of Stock Based Compensation Recognized in Consolidated Statement of Operations Stock-based compensation expense (including employee stock purchase plan expense) recorded in the accompanying condensed consolidated statements of operations for three months ended March 31, 2023 and 2022 was as follows:

 

 

Three Months Ended March 31,

 

 

 

2023

 

 

2022

 

Selling, general and administrative

 

$

91,523

 

 

$

192,903

 

Research and development

 

 

42,173

 

 

 

66,904

 

Cost of product and product-related services revenue

 

 

3,412

 

 

 

7,998

 

 

 

$

137,108

 

 

$

267,805

 

Summary of Stock Option Plans Activity

A summary of the Company’s stock option activity (including inducement award activity) for the three months ended March 31, 2023 is as follows:

 

 

Number of
Shares

 

 

Weighted-
Average
Exercise Price
Per Share

 

 

Weighted-
Average
Remaining
Contractual
Life (Years)

 

 

Aggregate
Intrinsic Value

 

Balance at December 31, 2022

 

 

76,099

 

 

$

84.73

 

 

 

8.3

 

 

$

 

Granted

 

 

666

 

 

 

4.35

 

 

 

 

 

 

 

Exercised

 

 

 

 

 

 

 

 

 

 

 

 

Forfeited

 

 

(3,693

)

 

 

10.57

 

 

 

 

 

 

 

Expired/Cancelled

 

 

(168

)

 

 

117.29

 

 

 

 

 

 

 

Balance at March 31, 2023

 

 

72,904

 

 

$

87.67

 

 

 

8.2

 

 

$

 

Exercisable at March 31, 2023

 

 

43,268

 

 

$

128.21

 

 

 

7.6

 

 

$

 

Summary of Restricted Stock Unit ("RSU") Award Activity

The following table summarizes restricted stock unit (“RSU”) award activity for the three months ended March 31, 2023:

 

 

Number of
Shares

 

 

Weighted-
Average
Grant Date
Fair Value
Per Share

 

Balance at December 31, 2022

 

 

1,249

 

 

$

44.40

 

Granted

 

 

 

 

 

 

Released

 

 

(312

)

 

 

44.38

 

Forfeited

 

 

 

 

 

 

Balance at March 31, 2023

 

 

937

 

 

$

44.40

 

Vested and unissued at March 31, 2023

 

 

208

 

 

$

62.42