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Stockholders' Equity - Summary of Material Factors Incorporated in Black-Scholes Model in Estimating Fair Value of Options Granted (Details) - $ / shares
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Common Stock    
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Expected dividend yield 0.00% 0.00%
Employee Stock Purchase Plan    
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Expected dividend yield 0.00% 0.00%
Maximum | Common Stock    
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Fair value of common stock on grant date $ 49.27 $ 75.00
Risk-free interest rate, Maximum 3.64% 1.20%
Expected volatility, Maximum 110.70% 107.30%
Expected term 5 years 9 months 18 days 6 years 1 month 6 days
Maximum | Employee Stock Purchase Plan    
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Fair value of common stock on grant date $ 49.80  
Risk-free interest rate, Maximum 2.25% 0.08%
Expected volatility, Maximum 96.70% 89.20%
Maximum | Employee Stock Purchase Plan | Common Stock    
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Fair value of common stock on grant date   $ 70.20
Minimum | Common Stock    
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Fair value of common stock on grant date $ 8.28 $ 48.84
Risk-free interest rate, minimum 1.53% 0.85%
Expected volatility, minimum 89.60% 104.20%
Expected term 5 years 6 months 5 years 2 months 12 days
Minimum | Employee Stock Purchase Plan    
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Fair value of common stock on grant date $ 6.00 $ 56.04
Risk-free interest rate, minimum 0.11% 0.04%
Expected volatility, minimum 64.90% 71.90%
Expected term 6 months 6 months