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Condensed Consolidated Statements of Cash Flows - USD ($)
9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Operating activities    
Net loss $ (16,901,876) $ (11,953,881)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 487,116 568,380
Accretion of discount on NuvoGen obligation (8,657) (9,206)
Provision for excess inventory 184,540 60,143
Amortization of SVB Term Loan discount and issuance costs 328,850 351,068
Stock-based compensation expense 637,121 1,000,368
Employee stock purchase plan expense 36,765 41,950
Non-cash operating lease expense 305,362 359,014
Accrued interest on available-for-sale securities investments (17,363) (18,394)
Gain on forgiveness of PPP Loan   (1,735,792)
(Gain) loss on abandonment and disposal of assets, net (104,000) 178,925
Changes in operating assets and liabilities:    
Accounts receivable 1,132,052 (597,489)
Inventory (183,536) (892,655)
Prepaid expenses and other (386,353) (300,469)
Accounts payable (937,550) (50,230)
Accrued liabilities (629,072) 205,015
Contract liabilities (20,652) 53,062
Operating lease liabilities (307,342) (378,355)
Net cash used in operating activities (16,384,595) (13,118,546)
Investing activities    
Purchase of property and equipment (23,043) (590,736)
Proceeds from the sale of property and equipment 104,000  
Maturities of available-for-sale securities 16,650,000 9,000,000
Purchase of available-for-sale securities (7,610,724) (17,871,203)
Net cash (used in) provided by investing activities 9,120,233 (9,461,939)
Financing activities    
Proceeds from ATM Offering, net of commissions of $0.3 million   10,665,819
Proceeds from March 2022 Purchase Agreement, net of $0.5 million of issuance costs 7,034,049  
Proceeds from LP Purchase Agreement   599,979
Payments on NuvoGen obligation (372,624) (379,431)
Payments on SVB Term Loan (5,955,882)  
Payments on SVB Term Loan Amendment issuance costs (14,282)  
Payments on deferred offering costs (80,692)  
Payments on financing leases (13,033) (18,040)
Proceeds from exercise of stock options   326
Taxes paid for net share settlement of restricted stock awards (10,792) (2,571)
Proceeds from shares purchased under stock purchase plans 23,327 53,437
Proceeds from exercise of pre-funded warrants 2,411  
Proceeds from insurance note 822,889  
Payments on insurance notes (530,790) (494,352)
Net cash provided by financing activities 904,581 10,425,167
Effect of exchange rates on cash (27,718) (12,848)
Decrease in cash and cash equivalents (6,387,499) (12,168,166)
Cash and cash equivalents at beginning of period 9,599,950 22,397,812
Cash and cash equivalents at end of period 3,212,451 10,229,646
Supplemental disclosure of noncash investing and financing activities    
Issuance of common stock upon conversion of Series A convertible preferred stock 1,402,430  
Issuance of common stock from cashless exercise of pre-funded warrants   145
2021 Insurance Note issued for insurance premiums   746,360
Gain on forgiveness of PPP Loan   1,735,792
Operating lease right-of-use assets obtained in exchange for operating lease liabilities   1,302,457
Carrying value of demonstration units transferred from property and equipment to inventory   16,128
Supplemental cash flow information    
Cash paid for interest 389,911 450,344
Cash paid for taxes $ 7,131 $ 12,665