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Stockholders' Deficit - Summary of Stock Option Plans Activity Including Inducement Award Activity (Details) - Employee Stock Option - USD ($)
6 Months Ended 12 Months Ended
Jun. 30, 2022
Dec. 31, 2021
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Number of Shares, Beginning Balance 559,336  
Number of Shares, Granted 93,000  
Number of Shares, Forfeited (49,220)  
Number of Shares, Expired/Cancelled (35,864)  
Number of Shares, Ending Balance 567,252 559,336
Number of Shares, Exercisable 313,518  
Weighted-Average Exercise Price Per Share, Beginning Balance $ 13.93  
Weighted-Average Exercise Price Per Share, Granted 1.66  
Weighted-Average Exercise Price Per Share, Forfeited 5.41  
Weighted-Average Exercise Price Per Share, Expired/Cancelled 33.37  
Weighted-Average Exercise Price Per Share, Ending Balance 11.43 $ 13.93
Weighted-Average Exercise Price Per Share, Exercisable $ 16.69  
Weighted-Average Remaining Contractual Life, Outstanding 8 years 1 month 6 days 8 years 2 months 12 days
Weighted-Average Remaining Contractual Life, Exercisable 7 years 4 months 24 days  
Aggregate Intrinsic Value, Balance $ 21,590 $ 30,267
Aggregate Intrinsic Value, Exercisable $ 4,562