INTANGIBLE ASSETS, Patents (Details) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2017	Jun. 30, 2016	Jun. 30, 2017	Jun. 30, 2016	Dec. 31, 2016
Finite-Lived Intangible Assets [Line Items]
Total	$ 198,411		$ 198,411		$ 216,781
Amortization expense	113,027	$ 199,526	202,334	$ 398,162
Future aggregate amortization expense for intangible assets [Abstract]
Total	198,411		198,411		216,781
Patents [Member]
Finite-Lived Intangible Assets [Line Items]
Intangible assets, gross	9,625,938		9,625,938		9,625,938
Less: accumulated amortization	(7,400,217)		(7,400,217)		(7,381,847)
Less: reserve for impairment	(2,027,310)		(2,027,310)		(2,027,310)
Total	198,411		198,411		216,781
Amortization expense	9,236	$ 118,461	18,370	$ 236,924
Future aggregate amortization expense for intangible assets [Abstract]
2017 (Six months)	18,674		18,674
2018	37,044		37,044
2019	37,044		37,044
2020	37,145		37,145
2021	37,044		37,044
2022 & Beyond	31,460		31,460
Total	198,411		198,411		216,781
Patents [Member] | Amlexanox (Aphthasol) [Member]
Finite-Lived Intangible Assets [Line Items]
Intangible assets, gross	2,090,000		2,090,000		2,090,000
Patents [Member] | Amlexanox (OraDiscA) [Member]
Finite-Lived Intangible Assets [Line Items]
Intangible assets, gross	6,873,080		6,873,080		6,873,080
Patents [Member] | OraDisc [Member]
Finite-Lived Intangible Assets [Line Items]
Intangible assets, gross	73,000		73,000		73,000
Patents [Member] | Hydrogel Nanoparticle Aggregate [Member]
Finite-Lived Intangible Assets [Line Items]
Intangible assets, gross	$ 589,858		$ 589,858		$ 589,858