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SHARE BASED COMPENSATION (Tables)
9 Months Ended
Sep. 30, 2016
SHARE BASED COMPENSATION [Abstract]  
Allocated share-based compensation expense
The following table summarizes share-based compensation related to stock options for the three and nine months ended September 30:

   
Three Months Ended
 September 30,
  
Nine Months Ended
 September 30,
 
   
2016
  
2015
  
2016
  
2015
 
Research and development
 $(3,079) $18,692  $5,914  $56,123 
Selling, general and administrative
  17,190   52,115   54,212   159,870 
  Total share-based compensation expense
 $14,111  $70,807  $60,126  $215,993 
Stock option activity
The following table summarizes the stock options outstanding and the number of shares of Common Stock subject to exercise as of September 30, 2016 and the changes therein during the nine months then ended:

   
Stock Options
  
Weighted Average Exercise Price per Share
 
Outstanding as of December 31, 2015
  1,664,573  $1.73 
Granted
  ---   --- 
Forfeited/cancelled
  (950,002) $1.27 
Exercised
  ---   --- 
Outstanding as of September 30, 2016
  714,571  $2.35 
Stock option grants outstanding and exercisable
The following table presents the stock option grants outstanding and exercisable as of September 30, 2016:

Options Outstanding
  
Options Exercisable
 
Stock Options Outstanding
  
Weighted Average Exercise Price per Share
  
Weighted Average Remaining Contractual Life in Years
  
Stock Options Exercisable
  
Weighted Average Exercise Price per Share
 
 422,500  $0.33   6.5   422,500  $0.33 
 240,000   1.15   8.0   240,000   1.15 
 52,071   24.20   0.9   52,071   24.20 
 714,571  $2.35   6.6   714,571  $2.35