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INTANGIBLE ASSETS (Tables)
12 Months Ended
Dec. 31, 2015
INTANGIBLE ASSETS [Abstract]  
Intangible assets
Intangible assets, net consisted of the following at December 31:

Intangible assets
 
2015
  
2014
 
  Patent - Amlexanox (Aphthasol®)
 $2,090,000  $2,090,000 
  Patent - Amlexanox (OraDisc™ A)
  6,873,080   6,873,080 
  Patent - OraDisc™
  73,000   73,000 
  Patent - Hydrogel nanoparticle aggregate
  589,858   589,858 
    9,625,938   9,625,938 
  Less: accumulated amortization
  (6,905,397)  (6,430,249)
  Intangible assets, net
 $2,720,541  $3,195,689 
Future aggregate amortization expense for intangible assets
The future aggregate amortization expense for intangible assets, remaining as of December 31, 2015, is as follows:

Calendar Years
 
Future Amortization
Expense
 
  2016
 $476,450 
  2017
  475,148 
  2018
  475,148 
  2019
  475,148 
  2020
  476,450 
  2021 & Beyond
  342,197 
  Total
 $2,720,541