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INTANGIBLE ASSETS (Tables)
12 Months Ended
Dec. 31, 2012
INTANGIBLE ASSETS [Abstract]  
Intangible assets
Intangible assets are comprised of patents acquired in October, 2005.  Intangible assets, net consisted of the following at December 31:

Intangible assets
 
2012
  
2011
 
Patent - Amlexanox (Aphthasol®)
 $2,090,000  $2,090,000 
Patent - Amlexanox (OraDisc™ A)
  6,873,080   6,873,080 
Patent - OraDisc™
  73,000   73,000 
Patent - Hydrogel nanoparticle aggregate
  589,858   589,858 
    9,625,938   9,625,938 
Less: accumulated amortization
  (5,479,953)  (5,003,503)
Intangible assets, net
 $4,145,985  $4,622,435 

Future aggregate amortization expense for intangible assets
Amortization expense for intangible assets was $476,450 and $769,132 for the years ended December 31, 2012 and 2011, respectively.  The future aggregate amortization expense for intangible assets, remaining as of December 31, 2012, is as follows:

Calendar Years
 
Future Amortization
Expense
 
2013
 $475,148 
2014
  475,148 
2015
  475,148 
2016
  476,450 
2017
  475,148 
2018 & Beyond
  1,768,943 
Total
 $4,145,985