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INTANGIBLE ASSETS
6 Months Ended
Jun. 30, 2011
INTANGIBLE ASSETS  
INTANGIBLE ASSETS
NOTE 8.
INTANGIBLE ASSETS

Intangible assets are comprised of patents acquired in October, 2005.  Intangible assets, net consisted of the following at June 30, 2011 and December 31, 2010:

Intangible assets
 
June 30, 2011
  
December 31, 2010
 
  Patent - Amlexanox (Aphthasol®)
 $2,090,000  $2,090,000 
  Patent - Amlexanox (OraDisc™ A)
  6,873,080   6,873,080 
  Patent - OraDisc™
  73,000   73,000 
  Patent - Hydrogel nanoparticle aggregate
  589,858   589,858 
    9,625,938   9,625,938 
  Less: accumulated amortization
  ( 4,640,549)  (4,234,371)
  Intangible assets, net
 $4,985,389  $5,391,567 

Amortization expense for intangible assets was $204,210 and $246,282 for the three months ended June 30, 2011 and 2010, respectively, and was $406,178 and $492,798 for the six months ended June 30, 2011 and 2010, respectively.

The future aggregate amortization expense for intangible assets, remaining as of June 30, 2011, is as follows:

Calendar Years
 
Future Amortization
Expense
 
  2011 (Six months)
 $362,954 
  2012
  476,450 
  2013
  475,148 
  2014
  475,148 
  2015
  475,148 
  2016 & Beyond
  2,720,541 
  Total
 $4,985,389